Tag: cognitive decline
Anticholinergic Burden with Tricyclic Antidepressants: Cognitive and Cardiac Risks
- By : Tamsin Riverton
- Date : Dec 9 2025
Tricyclic antidepressants like amitriptyline carry high anticholinergic burden, increasing risks of cognitive decline and heart rhythm problems. Safer alternatives exist for most patients, especially those over 50.
