Tag: cognitive decline

Anticholinergic Burden with Tricyclic Antidepressants: Cognitive and Cardiac Risks

Anticholinergic Burden with Tricyclic Antidepressants: Cognitive and Cardiac Risks

Tricyclic antidepressants like amitriptyline carry high anticholinergic burden, increasing risks of cognitive decline and heart rhythm problems. Safer alternatives exist for most patients, especially those over 50.

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