Tag: cognitive decline

Anticholinergic Burden with Tricyclic Antidepressants: Cognitive and Cardiac Risks

By : Tamsin Riverton
Date : Dec 9 2025

Tricyclic antidepressants like amitriptyline carry high anticholinergic burden, increasing risks of cognitive decline and heart rhythm problems. Safer alternatives exist for most patients, especially those over 50.

Tag: cognitive decline

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